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Help us reach our $5M goal to help with our revolutionary cure for Sickle Cell Disease!

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About the Campaign

Sickle cell disease is the most common inherited disorder among African-Americans; roughly 1 in 12 is a silent carrier and it affects 1 in 375 births. People with sickle cell disease endure bouts of extreme pain, frequent hospitalizations, and live with the knowledge that the disease is often fatal in one's 40s.

The Comprehensive Sickle Cell Center at The Children's Hospital of Philadelphia (CHOP) is one of the largest, most renowned centers for children and adolescents living with sickle cell disease. The Center encompasses both clinical care and research, with each enhancing the other: the large population of more than 1000 patients and families allows for research that quickly cycles back into improved treatments.

There are numerous sickle cell studies underway at CHOP to improve both lifespan and quality of life. These are taking place in such areas as pulmonary hypertension, which is a leading cause of fatalities in adults with sickle cell disease; stroke prevention; bone marrow transplantation; drug therapies; and the family and social factors that impact treatment. In addition, researchers at CHOP are on the brink of a medical breakthrough: a technique to prevent the symptoms of sickle cell disease.

Fetal surgeon Alan W. Flake, M.D., director of the Center for Fetal Research at CHOP, has spent nearly 30 years developing a pioneering procedure to transplant a mother's bone marrow stem cells into her developing fetus after prenatal testing confirms fetus has the disease at 8-10 weeks, effectively curing this devastating disease before the child is born. With sufficient philanthropic support, Dr. Flake is just three years away from clinical trials in humans.

Hope on the Horizon

Hope on the Horizon is a volunteer-driven campaign to raise crucial funds to support care and research at the Comprehensive Sickle Cell Center at The Children's Hospital of Philadelphia. The Sickle Cell Center is a national leader in treating children with sickle cell disease, a painful and life-limiting blood disorder that affects millions worldwide. Not only does CHOP offer expert clinical care to more than a thousand families living with sickle cell, but our researchers are making major breakthroughs that will help children live longer, healthier lives including a pioneering procedure to prevent all symptoms of the disease.

CHOP researchers are literally on the cusp of a cure for sickle cell disease, but we need your help. Donations to Hope on the Horizon will help us transform patients' lives and ultimately cure sickle cell disease. Donate now and join the fight for a cure.

Party 4 Peace

Dr. Kim Smith-Whitley and Dr. Alan W. Flake joined Charlie Mack and friends for a brunch hosted by Keystone Mercy as part of the Charlie Mack's Party 4 Peace Celebrity Weekend.  Attendees learned about the devastating effects of sickle cell disease and the promising research that CHOP is doing that may one day lead to a cure.